12th International Heidelberg Symposium on Stem Cells and Cancer – SCC2025

-
All Day
Download Poster
Download Program
BLAST-POSTER-Pasing-1600x900px

12th International Heidelberg Symposium on Stem Cells and Cancer – SCC2025

-
All Day
Download Poster
Download Program

About the Event SCC2025

The SCC 2025 international symposium focuses on latest highlights concerning the malignant transformation of stem cells in the blood and other organs, as well as new findings concerning the epigenetic regulation of healthy and diseased stem cells.

Scientific Program 2025

Get inspired by the best and brightest minds in Stem Cell & Cancer research at the International Symposium in Heidelberg.

Pre-Meeting: AML Workshop

Sep 14, 2025
11:00 - 12:35

AML Workshop Part 1

  • 11:00    Welcome and Opening Remarks (Carsten Müller-Tidow, Heidelberg)
  • 11:05    Novel stemness regulators in acute myeloid leukemia (Caroline Pabst, Heidelberg)
  • 11:30    MAC-Scoring predicts AMLs outcome with HMA/Venetoclax (Simon Renders & Alexander Waclawiczek, Heidelberg)
  • 11:55    Short Talk 1: Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells (Cornelius Pauli, Heidelberg)
  • 12:10    Immunotargeting of HSPCs and AML (Markus Manz, Zurich)
  • 12:35    LUNCH BREAK
Sep 14, 2025
13:20 - 14:30

AML Workshop Part 2

  • 13:30    Development of new therapies based on alloreactive responses to AML (Paresh Vyas, Oxford)
  • 13:55    Short Talk 2: Acute myeloid leukemia with UBTF tandem duplications respond to combined BCL-2 and RNA polymerase I inhibition with increased stemless and a quiescent-like state (Nesrine Aroua, Heidelberg)
  • 14:10    Cell therapy of myeloid malignancies (Saar Gill, Philadelphia)
  • 14:35    Podium Discussion: Future of AML therapies (invited workshop speakers & Andrew Wei)
  • 15:10    GROUP PICTURE AML WORKSHOP
  • 15:30     END OF CLINICAL WORKSHOP – COFFEE BREAK

Symposium

Sep 14, 2025
16:00 - 19:30

Symposium on Stem Cells and Cancer Part 1

  • 16:00    Welcome by Carsten Müller-Tidow & Andreas Trumpp
  • 16:10    Welcome Note by Michael Baumann, CEO& Scientific Director DKFZ
  • 16:15    Keynote Lecture: New direction and challenges in AML therapy (Andrew Wei, Melbourne)
  • 16:55    From single.cell landscapes to data-driven cancer taxonomies and precision medicine (Simon Haas, Berlin)
  • 17:25    Cancer neuroscience: how stem-like cancer cells are governed by neural features (Frank Winkler, Heidelberg)
  • 17:55    Mechanisms driving clonal hematopoiesis and impact on distal tissues (Margaret Goodell, Houston)
  • 18:25    WELCOME RECEPTION
  • 19:30    END OF DAY 1
Sep 15, 2025
09:00 - 10:40

Symposium on Stem Cells and Cancer Part 2

  • 09:00    Keynote Lecture: Therapeutic targeting of chromatin complexes in leukemia (Scott Armstrong, Boston)
  • 09:40    Novel approaches to target cell states in metastatic colorectal cancer (Rene Jackstadt, Heidelberg)
  • 10:10     Tumor cell plasticity in colorectal cancer (Fred de Sauvage, San Francisco)
  • 10:40    COFFEE BREAK
Sep 15, 2025
11:10 - 13:00

Symposium on Stem Cells and Cancer Part 3

  • 11:10    Systematic impact of metastasis over host metabolism (Salvador Aznar Benitah, Barcelona)
  • 11:40    Short Talk 3: Endosomal pH: A key driver in leukemic stem cell dynamics (Eleni Besiridou, Heidelberg)
  • 11:55    Acute myeloid leukemia genomics: Thinking outside of box (Ann-Kathrin Eisfeld, Columbus)
  • 12:25    Ten Lightning Talks – poster teasers – à 1 minute
  • 13:00    GROUP PICTURE, LUNCH BREAK, EXHIBITION
Sep 15, 2025
13:45 - 16:45

Symposium on Stem Cells and Cancer Part 4

  • 14:00    Poster Session 1 (odd numbered posters) and Exhibition
  • 15:15    Decoding and engineering T cell immunity against blood cancers (Mirco Friedrich, Heidelberg)
  • 15:45    Short Talk 4: Tet2 clonal hematopoiesis as a mechanistic driver of diet-induced liver cancer (Lina Merg, Heidelberg)
  • 16:00    DNMT3A-R882 mutation drives maladaptive myelopoiesis from human hematopoietic stem cells (Elisa Laurenti, Cambridge)
  • 16:30  COFFEE BREAK
Sep 15, 2025
17:15 - 18:00

Symposium on Stem Cells and Cancer Part 5

  • 17:00    Regulation of cellular plasticity in cancer (Moritz Mall, Heidelberg)
  • 17:30    Single cell and synthetic genomics of blood formation (Lars Velten, Barcelona)
  • 18:00    END OF DAY 2
Sep 16, 2025
09:00 - 11:10

Symposium on Stem Cells and Cancer Part 6

  • 09:00    Tissue stem cells: Acquiring, remembering and recalling past experiences in sickness and in health (Elaine Fuchs, New York)
  • 09:40    Metabolic signaling and metastasis (Sarah-Maria Fendt, Leuven)
  • 10:10    Modulation of bone marrow hematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study (Nina Cabezas-Wallscheid, Zurich)
  • 10:40    Perils and promise of unlocking stemness in the adult and aging brain (Ana Martin-Villalba, Heidelberg)
  • 11:10      COFFEE BREAK
Sep 16, 2025
11:40 - 13:10

Symposium on Stem Cells and Cancer Part 7

  • 11:40    Small non-coding RNAs drive leukemogenesis via rRNA modifications and chromatin functions (Carsten Müller-Tidow, Heidelberg)
  • 12:10    Stem Cell Pathways Aging and Cancer Evolution (Catriona Jamison, San Diego)
  • 12:40    Short Talk 5: Combination of phenotypic drug screening and a WNT signaling reporter to identify stemness-targeting drugs against colorectal cancer (Martina Zowada, Heidelberg)
  • 12:55   Ten Lightning Talks – poster teasers – à 1 minute
  • 13:25    LUNCH BREAK and EXHIBITION, 
Sep 16, 2025
14:00 - 17:15

Symposium on Stem Cells and Cancer Part 8

  • 14:15    Poster Session 2 (even numbered posters) and Exhibition
  • 15:30    IDH inhibition in AML (Paresh Vyas, Oxford)
  • 16:00    Targeting innervating peripheral neurons in pancreatic cancer (Andreas Trumpp, Heidelberg)
  • 16:30    Targeting RNA modifications in cancer (Michaela Frye, Heidelberg)
  • 17:00    Poster Prizes & Best Short Talk (Concluding Remarks: Carsten Müller-Tidow and Andreas Trumpp)
  • 17:30    END OF CONFERENCE
registry_opens

Key Topics at the Heidelberg Stem Cells and Cancer Conference

The conference will feature keynote lectures, poster sessions, and discussions on cutting-edge research, fostering collaboration between stem cell biologists and cancer researchers.
Become a Sponsor for SCC 2025

Cancer Stem Cells

Understanding the role of stem-like cells in tumor initiation, progression, and therapy resistance.

more details

Developmental Biology and Cancer

Comparing normal developmental processes with oncogenic transformation and tumor heterogeneity.

more details

Emerging Technologies and Translational Applications

Novel tools (e.g., organoids, CRISPR, AI) and their use in stem cell and cancer research.

more details

Epigenetics and Gene Regulation in Stem Cells and Cancer

Investigating how epigenetic modifications drive stem cell plasticity and cancer evolution.

more details

Immunology and Stem Cell-Cancer Interactions

The interplay between cancer stem cells, immune evasion, and immunotherapy approaches.

more details

Metabolism in Stem Cells and Tumors

Metabolic reprogramming in stem cells and cancer cells as a therapeutic target.

more details

Regenerative Medicine and Cancer

Harnessing stem cells for tissue repair while avoiding oncogenic risks.

more details

Single-Cell Technologies in Stem Cell and Cancer Research

Advances in single-cell genomics, transcriptomics, and proteomics to dissect cellular heterogeneity.

more details

Stem Cell Niches and Tumor Microenvironment

Exploring how the cellular and molecular environment influences stem cell behavior and cancer development.

more details

Therapy Resistance and Relapse Mechanisms

How cancer stem cells evade treatment and strategies to overcome resistance.

more details

Become a Sponsor for 2025

Join us in supporting cutting-edge cancer and stem cell research by becoming a sponsor of the 12th International Heidelberg Symposium.
Register here

12th International Heidelberg Symposium on Stem Cells and Cancer – SCC2025 – Speakers

Get inspired by the best and brightest minds in Stem Cell & Cancer research at the International Symposium in Heidelberg.

Andreas Trumpp

HI-STEM gGmbH & DKFZ

Heidelberg, Germany

more infos

Andreas Trumpp

Ann-Kathrin Eisfeld

The Ohio State University

Columbus, USA

more infos

Ann-Kathrin Eisfeld

Carsten Müller-Tidow

University Hospital Heidelberg

Heidelberg, Germany

more infos

Carsten Müller-Tidow

Catriona Jamieson

University of California

San Diego, USA

more infos

Catriona Jamieson
Keynote Speaker

Elaine Fuchs

The Rockefeller University

New York, USA

more infos

Elaine Fuchs

Fred de Sauvage

Genentech

San Francisco, USA

more infos

Fred de Sauvage

Margaret Goodell

Baylor College of Medicine Houston

Houston, USA

more infos

Margaret Goodell

Mirco J. Friedrich

HI-STEM gGmbH & DKFZ

Heidelberg, Germany

more infos

Mirco J. Friedrich

Paresh Vyas

University of Oxford

Oxford, England

more infos

Paresh Vyas

Rene Jackstadt

HI-STEM gGmbH & DKFZ

Heidelberg, Germany

more infos

Rene Jackstadt

Salavador Aznar Benitah

Institute for Research in Biomedicine (IRB Barcelona)

Barcelona, Spain

more infos

Salavador Aznar Benitah

Scott Armstrong

Dana-Farber Cancer Institute, USA

Boston, USA

more infos

Scott Armstrong

News & Updates

Further reknowned Speakers for the SCC2025 Symposium confirmed

Today we confirm additional Experts for SCC 2025: Courtney D. DiNardo, Simon Haas and Mirco Friedrich.

More reknowned Speakers confirmed

We are thrilled to announce additional distinguished speakers for SCC2025, taking place from September 14-16, 2025, at DKFZ in Heidelberg.…

2025 First reknowned Speakers confirmed

​We are pleased to announce the confirmed speakers for the 12th International Heidelberg Symposium on Stem Cells and Cancer (SCC2025),…

Other Events in

AML Clinical Workshop 2025

Symposium 2025

Our Organizers 2025